Welcome to the COOL lab at Oregon Health & Science University. We are dedicated to the advancement of biomedical imaging techniques in order to improve the diagnosis and treatment of eye diseases.
Future Vision Foundation selects Dr. David Huang for 2019 Future Vision award
Dr. Huang is the co-inventor of Optical Coherence Tomography (OCT), the most commonly used ophthalmic imaging technology at 30 million procedures per year. His seminal article on OTC has been cited over 13,000 times. Dr. Huang’s work is recognized as one of the most influential in the history of Ophthalmology.
Now accepting applications for
In this interview from ASRS 2018, Dr. Huang discusses his study exploring the use of OCT angiography (OCT-A) to identify patients at high risk for progression to exudation.
The mission of the Center for Ophthalmic Optics and Lasers (COOL) is to conserve, improve and restore vision through advances in laser and optical technology.
The Center for Ophthalmic Optics and Lasers (COOL) at the Casey Eye Institute, Oregon Health & Science University is an interdisciplinary research center that focuses on improving the diagnosis and treatment of eye diseases through advances in laser and optical technology. David Huang, MD, PhD, director of the COOL Lab, is a co-inventor of optical coherence tomography (OCT), which has become the most frequently used ophthalmic imaging procedure since 2003. The COOL Lab has pioneered many advances in ophthalmic OCT. In the anterior eye, COOL Lab researchers developed methods to map and measure the cornea, anterior chamber, angle, and lens and continues to lead the field in this area. This technology is now widely used to diagnose early keratoconus, narrow-angle glaucoma, ocular surface tumors, plan phototherapeutic keratectomy (PTK), and calculate intraocular lens power in patients with previous LASIK or other keratorefractive surgery. In the posterior segment, COOL Lab led the multi-center Advanced Imaging for Glaucoma bioengineering partnership, which was responsible for developing ganglion cell complex mapping for glaucoma evaluation, Doppler OCT to measure total retinal blood flow, and the first clinical investigation using OCT angiography. COOL Lab researchers developed a very efficient OCT angiography algorithm called “split-spectrum amplitude decorrelation angiography” (SSADA), which made the first commercial clinical OCT angiography system possible.
COOL Lab researchers are actively improving OCT angiography and applying it to the evaluation and management of age-related macular degeneration, diabetic retinopathy, inherited retinal degenerations, and ocular tumors. On the treatment side, the COOL lab is investigating the optimal technique for combining corneal collagen crosslinking and PTK for the treatment of keratoconus and is developing a laser thermal conjunctivoplasty device provides a safe, gentle, and fast healing procedure to treat conjunctivochalasis in an ophthalmologist’s office. The interdisciplinary team is able to perform interdisciplinary research from developing hardware (ultrahigh-speed OCT, laser surgical instrumentation), advancing signal and image processing algorithms, optimizing novel laser surgical techniques, conducting pilot clinical studies, to organizing large multi-site clinical studies. The COOL Lab also supports the Casey Reading Center with advanced OCT and OCT angiography reading software that can be used in a wide variety of clinical studies in retinal and optic nerve diseases.