Welcome to the COOL lab at Oregon Health & Science University. We are dedicated to the advancement of biomedical imaging techniques in order to improve the diagnosis and treatment of eye diseases.
The COOL Lab staff has found some fun ways to stay connected during COVID-19 modified operations!
GET TO KNOW OUR NEW FACULTY, STAFF & VISITING SCHOLARS
Dr Ramkailash Gujar is a Retina Research Fellow (Postdoctoral Scholar) at Casey Eye Institute since March 2022. He earned his graduation degree Bachelor of Optometry from All India Institute of Medical Sciences (AIIMS) , New Delhi, India. He also did Clinical fellowship in Optometry (Retina, Glaucoma and Low vision) from L V Prasad Eye Institute (LVPEI), Hyderabad, India. He recently completed his PhD in Translational Medicine and Surgery (Ophthalmology) from the University of Perugia, Italy in February 2022. Dr Ramkailash has worked as a Research Optometrist at LVPEI, Hyderabad. His research interests focus on artificial intelligence, optical coherence tomography angiography and other retinal imaging modalities in retinal vascular diseases.
Naixing(Nelson) Huang is a graduate student of the Biomedical Engineering Department at OHSU. He earned his bachelor's degree in Automation from Guangdong University of Technology(2022). His research interests are functional imaging and laser system development.
Dr. Siyu Chen earned his Ph.D. in Biomedical Engineering from Northwestern University in 2017. He completed his postdoctoral training at Massachusetts Institute of Technology and joined Oregon Health & Science University as Assistant Professor in 2022. Dr. Chen’s research projects investigated visible light optical coherence tomography (OCT), OCT retinal oximetry, ultrahigh resolution OCT and functional retinal imaging. His research interests include applying next generation imaging technology to facilitate the diagnosis, monitoring, and understanding of eye diseases.
COOL LAB'S LATEST NEWS
ARVO 2022 Annual Meeting
Yifan Jian Receives BrightFocus Foundation Macular Degeneration Research Award
Yifan Jian will receive a BrightFocus foundation award for his proposal, entitled "Mapping of Photoreceptor Nuclear Layer Using Volumetric Directional OCT: Applications in Age-Related Macular Degeneration" this July. His proposal was accepted by Vision Science's Review Committee after the completion of a very competitive review process.
Congrats to Shuibin Ni, Shanjida Khan & Jie Wang for receieving travel grants from ARVO.
Yali Jia, Ph.D., elected National Academy of Inventors Senior Member
Yali Jia, Ph.D., developed an algorithm that greatly improved the sensitivity of a highly efficient, non-invasive eye imaging technology called optical coherence tomographic angiography, or OCTA.
For that and other significant contributions, the National Academy of Inventors elected Jia, Jennie P. Weeks Professor of Ophthalmology and associate professor of biomedical engineering in the OHSU School of Medicine and Casey Eye Institute, an NAI Senior Member.
Election as an NAI Senior Member recognizes remarkable innovation producing technologies that have brought, or aspire to bring, real impact on the welfare of society. Senior Members also have success in patents, licensing, and commercialization, while educating and mentoring the next generation of inventors...(read more).
Congratulations Dr. David Huang for receiving the Greenberg Prize Award!
WASHINGTON, Dec. 3, 2020 /PRNewswire/ -- End Blindness 2020—an unprecedented joint effort by leading scientists and figures from the worlds of business, politics, culture, art, music and entertainment to rid the world of blindness—is about to mark a major milestone. On December 14, 2020, 13 pioneering scientists will share $3 million in prizes, from The Sanford and Sue Greenberg Prize to End Blindness, for their groundbreaking scientific and medical contributions to permanently and universally eradicate a condition that has plagued humans since the beginning of time. The hour-long streamed ceremony will be freely accessible and open to all at www.EndBlindness2020.com.
The Greenberg Prize awards ceremony will feature Art Garfunkel, Margaret Atwood, Al Gore, Michael Bloomberg, and Sen. Chris Coons among other luminaries. Musical performances will be provided by special guests. Grammy Award-winning jazz artist Diane Schuur, who was blind from birth due to Retinopathy of Prematurity, will share a few special words. Art-world legend Frank Stella will unveil a sculpture created in honor of the prize.
The Greenberg Prize ceremony will also feature a moving tribute to the late Ruth Bader Ginsburg, a longtime supporter of the End Blindness movement. The tribute will include exclusive footage of Justice Ginsburg reading from Hello Darkness, My Old Friend, the memoir of End Blindness 2020 co-founder Sanford D. Greenberg.
"While today's prize marks the culmination of years of challenging scientific work, in reality this prize is only the beginning of a journey of innovation and cooperation," Dr. Greenberg says. "Together, we are forging a new reality, one in which blindness will no longer determine the future of millions of people. We will end blindness, sooner than any of us can imagine, permanently and for everyone."
Recipients of The Greenberg Prize include members of the scientific and medical communities who have pioneered breathtaking advances in the fight to end the debilitating condition. Prize recipients are being honored in two categories: the Outstanding Achievement Prize, highlighting profound strides toward treating and curing blindness, and The Visionary Prize, providing funding for scientists whose research exhibits significant potential in ending this ancient scourge.
Outstanding Achievement Recipients:
Dr. Ravindran Ravilla, Aravind Eye Care System
Dr. G. N. Rao, The L.V. Prasad Eye Institute
Dr. Jean Bennett, Center for Advanced Retinal and Ocular Therapeutics, Department of Ophthalmology, Perelman School of Medicine at the University of Pennsylvania
Dr. Gustavo Aguirre, Division of Experimental Retinal Therapies, Department of Clinical Sciences & Advanced Medicine, School of Veterinary Medicine at the University of Pennsylvania
Dr. William Hauswirth, Department of Ophthalmology of the University of Florida
Dr. Albert Maguire, Center for Advanced Retinal and Ocular Therapeutics, Department of Ophthalmology, Perelman School of Medicine at the University of Pennsylvania
Dr. James Fujimoto, Department of Electrical Engineering and Computer Science Research Laboratory of Electronics, Massachusetts Institute of Technology
Dr. David Huang, Casey Eye Institute and Department of Ophthalmology, Oregon Health and Science University
Mr. Eric Swanson, Department of Electrical Engineering and Computer Science Research Laboratory of Electronics, Massachusetts Institute of Technology
Dr. Zhigang He, Boston Children's Hospital F.M. Kirby Neurobiology Center
Dr. Simon John, The Jackson Laboratory, Department of Ophthalmology, Columbia University
Dr. Botond Roska, Institute of Molecular and Clinical Ophthalmology Basel
Dr. Masayo Takahashi, RIKEN Center for Biosystems Dynamics Research; Vision Care, Inc. as part of Kobe Eye Center
"This is not just a prize but the 21st century equivalent of a moonshot, the effects of which will resound through history," according to Dr. Peter McDonnell, director of the Wilmer Eye Institute at the Johns Hopkins University School of Medicine and a member of the End Blindness National Governing Council. "Since time immemorial, blindness has been understood as an immutable fixture of the human condition. The great shift End Blindness has brought about demonstrates this is no longer the case. Together, we will end blindness—and sooner than anyone had ever imagined."
SOURCE The Greenberg Prize
Dr. Yali Jia awarded 2022 Biomedical Innovation Program funding
We are pleased to share the good news that Dr. Yali Jia has been named a 2022 Biomedical Innovation Program awardee in the Device, Diagnostic and Software track! Her project aims to transfer the OCT angiography technologies for diabetic retinopathy evaluation developed at the COOL Lab to the Casey Reading Center so they can be used in clinical trials.
The mission of the Center for Ophthalmic Optics and Lasers (COOL) is to conserve, improve and restore vision through advances in laser and optical technology.
The Center for Ophthalmic Optics and Lasers (COOL) at the Casey Eye Institute, Oregon Health & Science University is an interdisciplinary research center that focuses on improving the diagnosis and treatment of eye diseases through advances in laser and optical technology. David Huang, MD, PhD, director of the COOL Lab, is a co-inventor of optical coherence tomography (OCT), which has become the most frequently used ophthalmic imaging procedure since 2003. The COOL Lab has pioneered many advances in ophthalmic OCT. In the anterior eye, COOL Lab researchers developed methods to map and measure the cornea, anterior chamber, angle, and lens and continues to lead the field in this area. This technology is now widely used to diagnose early keratoconus, narrow-angle glaucoma, ocular surface tumors, plan phototherapeutic keratectomy (PTK), and calculate intraocular lens power in patients with previous LASIK or other keratorefractive surgery. In the posterior segment, COOL Lab led the multi-center Advanced Imaging for Glaucoma bioengineering partnership,
which was responsible for developing ganglion cell complex mapping for glaucoma evaluation, Doppler OCT to measure total retinal blood flow, and the first clinical investigation using OCT angiography. COOL Lab researchers developed a very efficient OCT angiography algorithm called “split-spectrum amplitude decorrelation angiography” (SSADA), which made the first commercial clinical OCT angiography system possible. COOL Lab researchers are actively improving OCT angiography and applying it to the evaluation and management of age-related macular degeneration, diabetic retinopathy, inherited retinal degenerations, and ocular tumors. On the treatment side, the COOL lab is investigating the optimal technique for combining corneal collagen crosslinking and PTK for the treatment of keratoconus and is developing a laser thermal conjunctivoplasty device provides a safe, gentle, and fast healing procedure to treat conjunctivochalasis in an ophthalmologist’s office. The interdisciplinary team is able to perform interdisciplinary research from developing hardware (ultrahigh-speed OCT, laser surgical instrumentation), advancing signal and image processing algorithms, optimizing novel laser surgical techniques, conducting pilot clinical studies, to organizing large multi-site clinical studies. The COOL Lab also supports the Casey Reading Center with advanced OCT and OCT angiography reading software that can be used in a wide variety of clinical studies in retinal and optic nerve diseases.
Presenting at ARVO 2019
RL Stevens Photography 2/21/2017
Yali Jia, PhD receiving award at ARVO 2019
Presenting at ARVO 2019