Each nomination celebrates an individual who has made a significant impact on the field, whether that is through a philanthropic initiative or their ongoing commitment to innovation. Categories include Champions of Change, Emerging Leaders, Inventors, Mentors, and Surgical Pioneers. Asked what he hopes to achieve in the next ten years, Dr Huang states, "I hope to help bring OCT angiography technology into the mainstream of clinical practice in glaucoma and retinal diseases. I would like to see the GoCheck Kids smartphone app being used to screen worldwide to catch refractive error and other amblyopia risk factors. I also have several new imaging and laser treatment ideas that I would like to bring to the stage of commercialization and clinical introduction."
Selected in recognition of her exceptional achievements in research, Dr. Yali Jia will receive the 2019 Discovery Award for Women in Science. Dr. Jia is among the most influential researchers working on developing optical coherence tomography angiography (OCTA). Her work has led to major breakthroughs that transitioned OCTA from a purely research technology to the clinic, which is a significant advancement for ophthalmology in general. The importance and quality of her research in OCTA is exemplary, and should serve as inspiration for the next generation of women scientists.
Yali Jia, PhD wins the 2019 ARVO Foundation/Pfizer Ophthalmics Carl Camras Translational Research Award
Yali Jia, PhD won this prestigious award which honors excellence in research and fundamental scientific discoveries, concepts and novel technologies. The discovery that each recipient is nominated for leads to, or has the promise of leading to, clinical applications. This award for young investigators working in areas of translational research honors Dr. Carl Camras, who is highly respected for his work as a glaucoma specialist and a research scientist. He is most widely recognized for developing prostaglandin analogues for the treatment of elevated IOP in patients with glaucoma. During his distinguished career, he took a personal interest in developing the next generation of eye and vision researchers.
Yali Jia, PhD is an Associate Professor of Ophthalmology and Biomedical Engineering at the Oregon Health & Science University (OHSU). Dr. Jia earned her PhD in Biomedical Engineering from OHSU in 2010 under the guidance of Dr. Ruikang Wang. Dr. Jia completed her post-doctoral training with Dr. David Huang at Casey Eye Institute in 2013. Dr. Jia is known for her innovations in optical coherence tomographic angiography (OCTA) and the application to eye diseases. She developed split-spectrum amplitude-decorrelation angiography (SSADA), which is a major breakthrough that transitioned OCTA from a purely research technology to the clinic. Her original paper on this subject, published in 2012, has been cited 900 times. She was awarded 3 NIH research project grants that supported the initial works that demonstrated clinical applications of OCTA in retinal diseases. She is the technical leader in Casey Reading Center. Her OCTA reading software (COOL-ART) has been used by several large clinical studies and many international collaborators. She has published more than 100 peer-reviewed journal articles with over 6000 citations. She has co-edited 3 books. Dr. Jia and her team are also pursuing research in other novel OCT technologies including the use of nanoparticles as OCT contrast agents, Doppler OCT to measure retinal blood flow, spectroscopic OCT to measure tissue oxymetry, and the use of artificial intelligence to detect and classify retinal pathologies.
Dr. Jia says of receiving this award, "This award is huge encouragement for me, women scientists and the OCT and OCTA community. I will continue to advance frontiers in my active research program and I believe the future of OCTA will have a major impact on the diagnosis and management of ocular diseases."
Yali Jia, PhD, was recognized by Technology Transfer and Business Development (TTBD) at OHSU as New Inventor of the Year. Associate professor of ophthalmology, Jia worked with TTBD to develop the split-spectrum amplitude-decorrelation angiography (SSADA) algorithm, which allows physicians to map ocular circulation down to the capillary level.
Established by Duke Eye Center Alumni, Kourosh Alexander Dastgheib, the Dastgheib Pioneer Award in Ocular Innovation Lecturer is awarded annually to someone who has made a major contribution in the field of Ophthalmology focused on something that has proved useful in real life.
Yali Jia, PhD Honored with a Research to Prevent Blindness William & Mary Greve Special Scholar Award
Oregon Health & Science University School of Medicine has been granted a $60,000 William & Mary Greve Special Scholar Award by Research to Prevent Blindness (RPB) to support eye research conducted by Yali Jia, PhD. The award, part of RPB's Special Scholar Program, is designed to support outstanding young scientists who are conducting research of unusual significance and promise.
RPB's Special Scholar awards were established in 1971. To date, the program has given awards to 221 up-and-coming vision research scientists in departments of ophthalmology at universities across the country.
Yali Jia, PhD Receives NIH Grant for Wide-Field and Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy
Yali Jia, PhD receives a 2017 NIH Grant for $487,587 for Wide-Field and Projection-Resolved Optical Coherence Tomography Angiography (OCTA) in Diabetic Retinopathy (DR). The program begins in 2017 and ends in 2021.
The OCTA technology used by previous studies is limited by the small fields of view (2.4-6 mm) and the projection artifacts in the deeper layers, which are caused by flowing blood cells in the more superficial vessels. The current proposal will overcome the previous limitations by improving both the hardware platform and software algorithms to obtain wide-field (WF) and projection-resolved (PR) OCTA.
Develop wide-field OCT system for imaging peripheral retinal circulation. We have developed a 200-kHz swept-source optical coherence tomography (SS-OCT) system. This system is ready for use in clinical studies. We propose to further increase system speed and develop automatic registration and montage algorithms to create ultrawide-field OCTA.
Improve the projection-resolved OCTA algorithm for imaging of retinal and choroidal plexuses. We have preliminarily demonstrated that separation of three retinal plexuses improved the detection of early vascular changes in DR. We will refine this algorithm and apply it to the WF-OCTA on the high-speed SS-OCT systems.
Quantify neovascularization and nonperfusion areas using WF- and PR-OCTA in DR. We will further optimize the automated quantification of all relevant DR endpoints, including nonperfusion of all vascular layers, neovascularization, cyst volume, and retinal thickness maps on both commercial and custom OCT systems proposed in this study.
Evaluate advanced OCTA for DR in clinical studies.
Election to NAI Fellow status is the highest professional distinction accorded solely to academic inventors who have demonstrated a prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development, and the welfare of society.
Academic inventors and innovators elected to the rank of NAI Fellow status have been nominated by their peers for outstanding contributions to innovation in areas such as patents and licensing, innovative discovery and technology, significant impact on society, and support and enhancement of innovation.
OHSU Casey Eye Institute researcher David Huang, M.D., Ph.D., has been awarded the 2017 Fritz J. and Dolores H. Russ Prize by the National Academy of Engineering. The Russ Prize recognizes an outstanding bioengineering achievement in widespread use that improves the human condition in areas ranging from biomedical instrumentation and prosthetic technologies to pharmaceutical processing and diagnostic technologies.
Huang, the Peterson Professor of Ophthalmology and professor of biomedical engineering, was a member of the James Fujimoto team that invented optical coherence tomography at the Massachusetts Institute of Technology. The National Academy of Engineering cites the team for dramatically improving the quality of life for people with diminished eyesight by leveraging creative engineering to invent imaging technology essential for preventing blindness and treating vascular and other diseases.
David Huang recognized by National Academy of Engineering
OCT has had a tremendous scientific, clinical, and economic impact on society. In the 25 years since its invention, OCT has become one of the most widely used technologies for imaging the human eye. Huang has contributed to the advances that make OCT an essential tool for treating blinding diseases ranging from macular degeneration to diabetic retinopathy. He has contributed to polarization-sensitive, swept-source, spectroscopic, and anterior eye OCT, as well as OCT angiography.
To view the Russ prize presentation, click the link below:
ARVO presents David Huang with the 2017
Dr. David L. Epstein Award
The award was created by the family of David L. Epstein, MD, to perpetuate and honor his commitment to the scientific understanding and cure of glaucoma through the support of promising clinician-scientists in exceptional research environments. It is the intent of the donors that this award further Dr. Epstein's long-standing determination and interest in solving the complex issues of glaucoma through well-conceived and executed scientific research focused on finding the causes and new treatments for the disease.